Exercise Your Way to Easing AI-Induced Aches
Published: Jan 15, 2024
Aromatase inhibitors are effective in breast cancer treatment but can cause joint pain and stiffness. Discover how exercise can be your ally in alleviating these discomforts.
Contents
The Painful Reality
Aromatase inhibitors (AIs) can lead to musculoskeletal issues, commonly known as AI-associated musculoskeletal syndrome (AIMSS). This syndrome includes symptoms like joint stiffness, bone pain, and even carpal tunnel syndrome. These side effects can be severe enough to cause some patients to discontinue treatment.
Exercise as a Solution
Regular exercise, especially resistance and strength training combined with moderate aerobic activity, has been shown to reduce pain severity associated with AIMSS. Studies indicate that women who engage in structured exercise programs report less pain and improved physical function, making exercise a compelling strategy for managing these side effects.

Crafting Your Workout Plan
To get started, aim for at least 150 minutes of moderate aerobic exercise weekly, coupled with twice-weekly strength sessions. Focus on exercises that build muscle strength and improve flexibility. Tailor your plan to your comfort level and consult with a healthcare professional for personalized guidance.
Frequently Asked Questions
Exercise reduces joint stiffness and improves physical function.
Resistance training and moderate aerobic activity are beneficial.
Aim for 150 minutes of aerobic exercise weekly, plus strength sessions.
The Bottom Line
Exercise is a powerful tool to combat the side effects of aromatase inhibitors.
References
- Irwin ML, Cartmel B, Gross CP, et al. Randomized exercise trial of aromatase inhibitor-induced arthralgia in breast cancer survivors. J Clin Oncol 2015; 33:1104.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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