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Duexis is a prescription tablet that combines ibuprofen (800 mg) and famotidine (26.6 mg). Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation in arthritic joints. Famotidine is an H2 blocker added to reduce the risk of ibuprofen-related stomach ulcers. The two ingredients work together so you can manage arthritis symptoms with built-in stomach protection.

Duexis is FDA-approved for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis in adults. It is specifically indicated for patients who are at risk for developing NSAID-associated upper gastrointestinal ulcers.

The standard dose of Duexis is one tablet taken three times daily. Tablets should be swallowed whole and not split, crushed, or chewed. Your physician will confirm the correct dosing schedule based on your individual health profile.

Common side effects can include nausea, heartburn, diarrhea, constipation, headache, and dizziness. As with all NSAIDs, more serious risks include cardiovascular events, gastrointestinal bleeding, and kidney effects. The famotidine component is included specifically to reduce the risk of stomach ulcers. Contact your doctor promptly if you experience chest pain, black or tarry stools, or significant stomach pain.

Duexis should not be used by patients who have had an allergic reaction (including hives or asthma) to aspirin or other NSAIDs, those with severe kidney disease, those who have recently had or are about to have coronary artery bypass graft (CABG) surgery, or women in the third trimester of pregnancy. Your physician will review your complete medical history before prescribing.

Yes. Duexis can interact with blood thinners such as warfarin, other NSAIDs or aspirin, ACE inhibitors, ARBs, diuretics, lithium, methotrexate, and certain antidepressants. Always provide your Doctronic physician with a full list of current medications, supplements, and over-the-counter drugs before starting Duexis.

Doctronic uses an AI-guided evaluation to collect detailed information about your symptoms and medical history. A licensed physician then reviews your case, determines whether a treatment is appropriate, and creates a personalized treatment plan. The entire process is completed online, so you can get care from the comfort of your home.

Yes. Doctronic connects you with fully licensed physicians who are board-certified in their fields. All consultations are doctor-reviewed and audited for clinical accuracy, and the platform is HIPAA-compliant to protect your personal health information. Doctronic is available to adults 18 and older in any U.S. state.