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Trulicity (dulaglutide) is a once-weekly injectable GLP-1 receptor agonist. It works by stimulating insulin secretion when blood sugar is elevated, suppressing glucagon release, and slowing gastric emptying, all of which help lower blood glucose levels in adults with type 2 diabetes.

Trulicity is injected subcutaneously once a week using a single-dose prefilled pen. It can be injected into the abdomen, thigh, or upper arm. You do not need to mix or measure the medication, and the pen does not require refrigeration for short-term storage.

The most commonly reported side effects include nausea, diarrhea, vomiting, abdominal pain, and decreased appetite. These effects are usually most pronounced when starting treatment or increasing the dose, and often improve over time.

Trulicity is not recommended for people with a personal or family history of medullary thyroid carcinoma, or those with Multiple Endocrine Neoplasia syndrome type 2. It should not be used to treat type 1 diabetes or diabetic ketoacidosis, and caution is required in patients with a history of pancreatitis.

Many people experience modest weight loss while taking Trulicity, likely due to reduced appetite and slower gastric emptying. However, Trulicity is approved for blood sugar management in type 2 diabetes, not as a primary weight-loss medication.

Most patients begin on a 0.75 mg once-weekly dose. After four weeks, the dose may be increased to 1.5 mg weekly if additional glycemic control is needed. Higher doses of 3 mg and 4.5 mg are also available for patients who need further reduction in HbA1c.

Doctronic uses AI-driven evaluation to gather detailed information about your health and symptoms. A licensed physician then reviews your information and, if appropriate, creates a personalized treatment plan that may include a prescription sent to your pharmacy.

Yes. Doctronic connects patients with fully licensed physicians whose decisions are doctor-reviewed and audited for quality. The platform is HIPAA-compliant, and care is available to adults 18 and older in any U.S. state.