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Wegovy is a once-weekly injectable prescription medication containing semaglutide 2.4 mg. It is a GLP-1 receptor agonist that mimics a natural gut hormone to reduce appetite, slow gastric emptying, and promote feelings of fullness. This leads to reduced calorie intake and, over time, significant weight loss when combined with a reduced-calorie diet and increased physical activity.

Wegovy is FDA-approved for adults with a BMI of 30 or greater, or a BMI of 27 or greater who also have at least one weight-related health condition such as high blood pressure, type 2 diabetes, or high cholesterol. A licensed physician will review your full health history to confirm eligibility.

Wegovy is administered as a once-weekly subcutaneous (under the skin) injection, typically in the abdomen, thigh, or upper arm. Treatment starts at a low dose of 0.25 mg per week and is gradually increased over approximately 16 weeks to the full maintenance dose of 2.4 mg per week to help minimize side effects.

The most commonly reported side effects are gastrointestinal in nature and include nausea, vomiting, diarrhea, constipation, and stomach pain. These effects are often most pronounced when starting or increasing the dose and tend to improve over time. Your physician can advise on strategies to manage these symptoms.

Wegovy carries a boxed warning regarding a potential risk of thyroid C-cell tumors observed in animal studies, so it is contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). It should also be used with caution in people with a history of pancreatitis, gallbladder disease, or severe kidney problems. A physician will screen for these conditions before prescribing.

In clinical trials, adults using Wegovy alongside lifestyle changes lost an average of approximately 15% of their body weight over 68 weeks, compared to about 2.4% with placebo. Individual results vary based on starting weight, adherence to medication, diet, and activity level.

Wegovy can be used in adults with type 2 diabetes who also meet the weight criteria, though its sister medication Ozempic (semaglutide 1 mg) is specifically approved for blood sugar management in type 2 diabetes. If you have type 2 diabetes, your physician will carefully review your current diabetes medications for potential interactions and adjust your treatment plan accordingly.

Doctronic uses an AI-guided evaluation to gather your health history and symptoms, which is then reviewed by a licensed, board-certified physician. If appropriate, the physician creates a personalized treatment plan that may include a prescription. All care is doctor-reviewed and audited, and the platform is fully HIPAA-compliant, so your health information is protected.