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Addison's Disease, also called primary adrenal insufficiency, is a condition in which the adrenal glands do not produce enough cortisol and, in many cases, not enough aldosterone. It is most commonly caused by an autoimmune attack on the adrenal cortex.

Common symptoms include chronic fatigue, muscle weakness, weight loss, low blood pressure, salt cravings, nausea, darkening of the skin (hyperpigmentation), and dizziness when standing. Symptoms often develop slowly and can be easy to miss at first.

An adrenal crisis is a life-threatening emergency that can occur when cortisol levels drop severely, often triggered by illness, injury, or missed medication. Symptoms include sudden severe weakness, vomiting, low blood pressure, and confusion. It requires immediate emergency medical care with intravenous hydrocortisone and fluids.

Diagnosis typically involves blood tests checking cortisol, ACTH (adrenocorticotropic hormone), sodium, and potassium levels, followed by an ACTH stimulation test to confirm that the adrenal glands are not responding normally. Imaging of the adrenal glands may also be ordered.

Most people with Addison's Disease take daily oral hydrocortisone or another glucocorticoid to replace cortisol, and often fludrocortisone to replace aldosterone. Doses typically need to be increased during illness, surgery, or significant stress, a process called sick-day dosing or stress dosing.

There is no cure for autoimmune Addison's Disease. It is a lifelong condition requiring ongoing hormone replacement. However, with consistent treatment and monitoring, the vast majority of people manage their condition well and maintain good quality of life.

Doctronic uses AI-powered evaluation to gather your symptoms and medical history, which is then reviewed by a licensed physician. The physician creates a personalized treatment plan, which may include prescriptions, referrals, or follow-up guidance, all designed to support your care.

Yes. Doctronic works exclusively with licensed physicians who review and audit all care plans. The platform is HIPAA-compliant and designed to meet the same standards of safety and accuracy you would expect from an in-person medical visit. All adults 18 and older in any U.S. state are eligible to use the service.