Get Synjardy Online

Synjardy combines two proven diabetes medicines in one daily pill. Get a clinician evaluation online and, if appropriate, a prescription sent to your pharmacy without leaving home.


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What Is Synjardy?

Synjardy (empagliflozin-metformin) is a prescription medication used to manage type 2 diabetes in adults. It works by combining an SGLT2 inhibitor that causes the kidneys to excrete excess glucose in the urine with a biguanide that reduces hepatic glucose production and improves insulin sensitivity. With the right dose and ongoing monitoring, most patients achieve meaningful reductions in blood sugar and HbA1c while benefiting from a single convenient tablet.

  • Two complementary mechanisms in one tablet for blood sugar control
  • Get personalized guidance from doctor-trained AI
  • Explore treatment and prescription options

Is Online Synjardy Treatment Right for You?

Synjardy is prescribed for adults with type 2 diabetes whose blood sugar is not adequately controlled by empagliflozin or metformin alone. It is not indicated for type 1 diabetes or diabetic ketoacidosis.

Because Synjardy affects kidney function and carries a risk of lactic acidosis, your prescribing physician will review your kidney function (eGFR), any history of renal or hepatic impairment, and any medications that may interact before approving your treatment plan.

  • Diagnosed with type 2 diabetes
  • Get personalized guidance from AI and clinicians
  • Explore treatment and prescription refill options
  • Access care from home, often the same day
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Diagnosed with type 2 diabetes Fasting blood glucose or HbA1c above goal Experiencing high blood sugar symptoms (thirst, frequent urination, fatigue) Need a prescription refill Adults 18+ in any U.S. state

How Type 2 Diabetes Treatment Works at Doctronic


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Doctronic answers your health questions with personalized medical insights and helps our doctors create a better treatment plan for you.


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Book a $39 telehealth appointment (or copay) within 30 minutes. Our doctors create personalized treatment plans with prescriptions when needed.


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Our doctors prescribe non-controlled medications in all 50 states and send prescriptions to your pharmacy for same-day pickup.

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Frequently asked questions

Synjardy contains empagliflozin and metformin. Empagliflozin is an SGLT2 inhibitor that tells your kidneys to remove excess glucose through urine. Metformin is a biguanide that reduces the amount of glucose your liver releases and helps your body use insulin more effectively. Together they lower fasting and post-meal blood glucose and reduce HbA1c.

Synjardy is taken twice daily with meals to reduce gastrointestinal side effects. Your physician will prescribe the strength (5 mg/500 mg, 5 mg/1000 mg, 12.5 mg/500 mg, or 12.5 mg/1000 mg) appropriate for your current glucose levels and kidney function. Always follow your prescriber's specific instructions.

Common side effects include nausea, diarrhea, stomach upset, and urinary tract or genital yeast infections. A rare but serious risk is lactic acidosis, a buildup of lactic acid in the blood that is more likely in people with kidney or liver problems. Contact your doctor promptly if you experience unusual muscle pain, difficulty breathing, or stomach discomfort.

Synjardy is not appropriate for people with type 1 diabetes, diabetic ketoacidosis, severe kidney disease (eGFR below 30 mL/min), or serious liver impairment. It should be temporarily stopped before contrast dye procedures or major surgeries. Tell your doctor about all medications you take, as some drugs can interact with metformin or empagliflozin.

Yes. Regular blood glucose checks and periodic HbA1c testing are important to confirm that Synjardy is working and that your dose remains appropriate. Your physician may also order kidney function tests (serum creatinine or eGFR) at least once a year because empagliflozin depends on adequate renal function to work.

Synjardy is often used alongside other antidiabetic agents such as insulin or GLP-1 receptor agonists when additional glucose lowering is needed. Combining it with insulin or sulfonylureas increases the risk of low blood sugar, so your doctor may adjust those doses. Never add or stop medications without first consulting your prescriber.

Doctronic uses an AI-guided evaluation to gather detailed information about your health history and symptoms. A licensed physician then reviews your responses, and if treatment is appropriate, creates a personalized treatment plan that can include a prescription sent directly to your preferred pharmacy.

Yes. Doctronic connects you with fully licensed physicians whose consultations are doctor-reviewed and audited for quality. The platform is HIPAA-compliant, keeping your personal health information private and secure throughout the entire process.