Clarinex (Desloratadine) Storage and Expiration: Does It Still Work?
Understanding Desloratadine Expiration DatesDesloratadine, the active ingredient in Clarinex, follows FDA requirements for expiration date testing and labeling. [...]
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Medically reviewed by Oghenefejiro Okifo | MD , Harvard Medical School | Henry Ford Hospital - Detroit, MI on December 7th, 2023. Updated on March 18th, 2026
Collagen fibers form during wound healing within 3-21 days, creating tissue that's 80% as strong as original skin but lacks the organized structure of normal dermis.
Keloid formation occurs 3-10 times more frequently in individuals with darker skin tones, particularly those of African, Asian, or Hispanic descent, due to increased melanocyte activity.
Hypertrophic variants remain within wound boundaries and may flatten over 12-18 months, while keloids extend beyond original injury sites and rarely improve without intervention.
Silicone gel sheeting applied 12-24 hours daily for 2-3 months can reduce thickness by up to 86% and improve texture when started within 2 weeks of wound closure.
Steroid injections using triamcinolone (10-40 mg/mL) every 4-6 weeks can flatten raised tissue by 50-100%, though hypopigmentation occurs in 30% of patients.
Scars are a natural part of the body's healing process, forming when the skin and other tissues are damaged. Most wounds, except for very minor ones, result in some degree of scarring. Scars can be caused by accidents, diseases, skin conditions like acne, or surgeries.
When the dermis, the deep, thick layer of skin, is damaged, the body produces new collagen fibers to mend the damage. This results in a scar that has a different texture and quality than the surrounding tissue. Scars form after a wound is completely healed.
There are several different types of scars:
Flat and pale scars: Most scars have this appearance.
Raised scars: When the body produces too much collagen, hypertrophic or keloid scars can form. These scars are more common in younger and dark-skinned people.
Sunken or pitted scars: These scars occur when underlying structures supporting the skin, such as fat or muscle, are lost. Some surgical scars and acne scars have this appearance.
Stretched scars: These scars result when the skin stretches rapidly, like during growth spurts or pregnancy, or when the skin is under tension near a joint during the healing process.
Although scars cannot be completely removed, their appearance can be improved to some extent. Here are some methods for treating scars:
Topical treatments: Over-the-counter products like vitamin E, cocoa butter cream, silicone gel, onion extract, Vaseline, and Aquaphor may be somewhat effective in helping to heal scars.
Surgery: While surgery cannot remove a scar, it can alter its shape or make it less noticeable. However, surgery is not recommended for raised scars due to the risk of recurrence or more severe scarring.
Steroid injections: A course of steroid injections into a scar may help flatten it and soften the appearance of keloid or hypertrophic scars.
5-fluorouracil (5-FU) or bleomycin injections: These medications can be injected into scars to reduce their size and ease itchiness and pain.
Radiotherapy: Low-dose, superficial radiotherapy is used in extreme cases to prevent recurrence of severe keloid and hypertrophic scarring, but it may have long-term side effects.
Dermabrasion and microdermabrasion: These treatments involve removing the surface layers of the skin to blend in scar irregularities.
Laser resurfacing: Similar to dermabrasion, this procedure uses lasers to remove the surface layers of the skin or work on the collagen in the dermis for more subtle results.
Filler injections: These temporary treatments can raise sunken scars to the level of surrounding skin.
Microneedling: This procedure involves making many small puncture holes in the skin to stimulate collagen production and introduce collagen stimulators or other products to reduce the appearance of scars.
Cryosurgery: Freezing the scar can reduce its size, pain, itchiness, hardness, and discoloration. This may be combined with steroid or 5-FU injections.
If you have concerns about your scars, consult with a dermatologist or plastic surgeon to discuss the best treatment options for your specific case. Remember, while scars cannot be completely removed, there are many ways to improve their appearance and reduce any discomfort associated with them. For more information, visit the WebMD page on scars.
Early intervention within the first few weeks of healing offers the best opportunity to minimize formation and improve final appearance. Consistent treatment for 3-6 months is essential, as tissue remodeling continues for up to two years after initial injury. If you're noticing raised, discolored, or painful tissue changes, Doctronic can help you explore the most effective treatment options.
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