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Saxenda is a prescription injectable medication containing liraglutide 3 mg. It works by activating GLP-1 receptors in the brain and gut, which helps reduce appetite, slow stomach emptying, and lower overall calorie intake, leading to gradual weight loss over time.

Saxenda is approved for adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related condition such as type 2 diabetes, high blood pressure, or high cholesterol. It is used alongside a reduced-calorie diet and regular physical activity.

Saxenda is injected once daily under the skin of the abdomen, thigh, or upper arm. The dose is started low and gradually increased over five weeks to the target dose of 3 mg per day to minimize gastrointestinal side effects.

The most common side effects include nausea, diarrhea, constipation, vomiting, and decreased appetite. These are often most noticeable when starting or increasing the dose and tend to improve over time for most patients.

Saxenda carries a boxed warning about the risk of thyroid C-cell tumors observed in animal studies; it should not be used in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Other serious risks include pancreatitis, gallbladder problems, and heart rate increases. Your physician will review your history carefully before prescribing.

In clinical trials, patients using Saxenda along with lifestyle changes lost an average of about 8 percent of their body weight over 56 weeks, compared to about 2.6 percent with placebo and lifestyle changes. Individual results vary based on adherence, diet, and activity level.

Yes, Saxenda can be prescribed for adults with type 2 diabetes who meet the BMI criteria. However, patients with diabetes who are taking insulin or sulfonylureas should be monitored carefully, as combining these medications with Saxenda may increase the risk of low blood sugar.

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