Does Lexapro Cause Erectile Dysfunction? Understanding Antidepressant Sexual Side Effects

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on February 4th, 2026.

Key Takeaways

  • Lexapro may cause sexual dysfunction in up to 30% of users

  • Sexual side effects may persist even after stopping medication

  • Not all antidepressants impact sexual function equally

  • Consulting a healthcare provider can help manage potential side effects

Depression impacts millions of people, and medications like Lexapro offer critical support for mental health. However, understanding potential sexual side effects is important for patients considering or currently taking antidepressants. Erectile dysfunction is a common concern for men using selective serotonin reuptake inhibitors (SSRIs) like Lexapro.

Sexual health is an essential aspect of overall well-being, and medication should not compromise your quality of life. While Lexapro can be an effective treatment for depression and anxiety, it's crucial to understand how it might impact your sexual function.

How Lexapro Affects Sexual Function

Lexapro, a commonly prescribed antidepressant, can cause sexual side effects in some patients. Sexual dysfunction impacts between 25% to 73% of SSRI users, with symptoms potentially including:

  • Reduced sexual desire

  • Difficulty achieving or maintaining erections

  • Delayed or absent orgasm

  • Decreased genital sensitivity

The mechanism behind these side effects relates to how SSRIs interact with serotonin levels in the brain. By increasing serotonin, these medications can inadvertently impact other neurochemical processes that regulate sexual response.

Prevalence of Sexual Side Effects with Lexapro

Research indicates that approximately 30% of Lexapro users may experience some form of sexual dysfunction. Understanding medication interactions can help patients make informed decisions about their treatment.

The likelihood of experiencing sexual side effects can depend on several factors:

  • Dosage of medication

  • Individual body chemistry

  • Duration of treatment

  • Concurrent health conditions

Managing Sexual Side Effects

If you're experiencing sexual dysfunction while taking Lexapro, several strategies can help:

Consulting Your Healthcare Provider

Open communication with your healthcare provider is crucial. They might:

  • Adjust medication dosage

  • Switch to a different antidepressant

  • Recommend complementary treatments

Potential Treatment Approaches

Some approaches to managing sexual side effects include:

Comparing Antidepressant Sexual Side Effects

Antidepressant

Sexual Dysfunction Risk

Common Sexual Side Effects

Lexapro

Moderate

Erectile dysfunction, reduced libido

Prozac

Low to Moderate

Delayed orgasm, decreased arousal

Zoloft

Low

Mild sexual function changes

Paxil

High

Significant erectile dysfunction

Frequently Asked Questions

Most sexual side effects are temporary and resolve after adjusting medication or treatment.

Side effects can vary but often improve within a few weeks to months of starting treatment.

Wellbutrin and some newer antidepressants may have fewer sexual dysfunction risks.

Never stop medication without consulting your healthcare provider first.

Exercise, stress reduction, and healthy lifestyle choices can potentially mitigate some sexual side effects.

The Bottom Line

Sexual health is an important consideration when managing depression. While Lexapro can cause sexual side effects, many patients find successful strategies to maintain both mental and sexual wellness.

Ready to meet your AI doctor? Get started with Doctronic today.

Related Articles