Get Zostrix Online

Zostrix (capsaicin cream) is a topical prescription option for neuropathic pain relief. Get evaluated by a licensed physician online and receive a personalized treatment plan without leaving home.

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Medications We Prescribe for Neuropathic Pain

Zostrix

Capsaicin Cream

First-line topical agent for neuropathic pain; depletes substance P at peripheral nerve endings for localized relief.

Get Zostrix online Drug Info

Lidoderm

Lidocaine Patch 5%

Topical anesthetic patch commonly used for post-herpetic neuralgia and localized neuropathic pain.

Get Lidoderm online Drug Info

Qutenza

Capsaicin Patch 8%

High-concentration capsaicin patch for more severe neuropathic pain; applied in a clinical setting.

Get Qutenza online Drug Info

Neurontin

Gabapentin

Oral anticonvulsant widely used as a first-line systemic treatment for neuropathic and nerve pain.

Get Neurontin online Drug Info

Pricing that won't make you sick

Chat for free, see an online doctor for $39/visit, or renew a prescription online for as low as $0

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These are stories from real users who turned to Doctronic for answers when it mattered most.

  • Preparing for a doctor visit
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  • Understanding a diagnosis
  • Managing chronic illness
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  • A second opinion
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How Neuropathic Pain Treatment Works at Doctronic


Start a Free Chat With Doctronic

Doctronic answers your health questions with personalized medical insights and helps our doctors create a better treatment plan for you.


Meet With a Licensed Doctor For Treatment

Book a $39 telehealth appointment (or copay), with an average wait of about 5 minutes. Our doctors create personalized treatment plans with prescriptions when needed.


Pick Up Your Prescription

Our doctors prescribe non-controlled medications in all 50 states and send prescriptions to your pharmacy for same-day pickup.

Hear from our users

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Didn't even have to Leave Home!

I was able to see a doctor without getting up and going to the doctors office. The doctor was super helpful and prescribed me the medication I needed straight to the pharmacy I use. I highly recommend using Doctronic. I was given a solution a lit quicker than I would going and seeing my primary doctor. 5/5 stars. Will recommend to friends and family!


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I think it was great because the diagnosis they gave for my partner's symptoms were exactly what he said he's been diagnosed with before so on the advice of what was suggested to do we're going to the emergency room right now. Thank you


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Confirmed what I thought was causing…

Confirmed what I thought was causing some of my symptoms. I will discuss this with my primary on my next appointment.


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It actually felt like I was talking to…excellent experience

It actually felt like I was talking to a doctor. They asked all the questions I would expect to hear and instead of advising me to rush to an ER, it gave me good practical solutions to try now before escalating it to a doctor visit. It also offered for me to conduct an immediate consultation or to schedule a time for an virtual appointment with a licensed doctor which I am extremely grateful for and fully intend to use this option if my condition doesn't improve as well as for future needs. Nothing is worse than waiting in a doctor's office for hours just to spend a fortune for two minutes with an actual physician. Thank you for your free recommendations and for not just giving me the canned response of getting immediate medical attention.


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JustAnswer Customer June 23, 2026

What Is Zostrix?

Zostrix (capsaicin) is a prescription-strength topical medication used to manage neuropathic pain, including post-herpetic neuralgia and diabetic peripheral neuropathy. It works by depleting substance P, a neuropeptide that transmits pain signals from peripheral nerve endings to the central nervous system, resulting in desensitization of the pain fibers over time. With the right application schedule and consistent use, many patients experience meaningful, lasting reduction in localized pain.

  • Targets peripheral pain fibers by depleting substance P for localized neuropathic pain relief
  • Get personalized guidance from doctor-trained AI
  • Explore treatment and prescription options

Is Online Zostrix Treatment Right for You?

Zostrix (capsaicin cream) may be appropriate for adults experiencing neuropathic pain conditions such as post-herpetic neuralgia, diabetic peripheral neuropathy, or musculoskeletal pain who have not achieved adequate relief from other therapies. A Doctronic physician will review your symptoms, medical history, and any prior treatments to determine whether Zostrix is right for you.

Because neuropathic pain often involves underlying conditions affecting the nervous system or metabolic health, your provider will also consider your full medical background, including any history of diabetes, shingles, nerve injury, or skin conditions at the intended application site, before prescribing.

  • Diagnosed with neuropathic pain, post-herpetic neuralgia, or diabetic peripheral neuropathy
  • Get personalized guidance from AI and clinicians
  • Explore treatment and prescription refill options
  • Access care from home, often the same day
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Diagnosed with neuropathic pain or post-herpetic neuralgia Localized burning or shooting pain in a specific area Persistent skin-surface pain that disrupts daily activity Need a prescription refill Adults 18+ in any U.S. state

Frequently asked questions

Zostrix contains capsaicin, the active compound found in chili peppers. Applied to the skin, it works by repeatedly stimulating and then depleting substance P in peripheral pain nerve fibers, which reduces their ability to transmit pain signals over time. Regular use typically leads to progressive pain reduction in the treated area.

Zostrix is typically applied three to four times daily to the affected area. A localized burning or stinging sensation is common during the first one to two weeks as substance P is depleted. Most patients begin to notice meaningful pain relief after two to four weeks of consistent use.

Yes. Post-herpetic neuralgia, the persistent nerve pain that can follow a shingles outbreak, is one of the most studied indications for capsaicin cream. Clinical evidence supports its use for reducing burning and allodynia in affected skin areas after the shingles rash has healed.

The most common side effect is a transient burning, stinging, or redness at the application site, especially during the first week or two. Avoid contact with eyes, mucous membranes, and broken or irritated skin. Wash hands thoroughly after each application unless the hands are the treated area. Severe or worsening skin reactions should be reported to your provider.

Avoid applying heat, tight bandages, or other topical products to the treated area immediately after applying Zostrix, as these can intensify the burning sensation. Do not apply before bathing in hot water. Wearing gloves during application is recommended if you are not treating your hands.

Zostrix acts locally on the skin and is minimally absorbed systemically, making it generally well tolerated in patients with diabetes or kidney disease. However, diabetic patients should be cautious if neuropathy has reduced skin sensation, as they may not notice irritation. Your Doctronic physician will review your full health history before prescribing.

Doctronic uses an AI-powered evaluation to gather detailed information about your symptoms and medical history. A licensed physician then reviews your case, makes a clinical determination, and, if appropriate, creates a personalized treatment plan that may include a prescription. The entire process is designed to be fast, thorough, and convenient.

Yes. Doctronic works exclusively with licensed physicians who are board-certified in their specialties. All consultations are HIPAA-aligned, and every treatment decision is doctor-reviewed and audited for safety and accuracy. Doctronic is available to adults 18 and older in any U.S. state.