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Permethrin is a synthetic pyrethroid that disrupts sodium channel function in the nerve cell membranes of Sarcoptes scabiei mites and their eggs. This causes paralysis and death of the parasite. A single application of 5% permethrin cream left on the skin for 8 to 14 hours is typically effective at eliminating the infestation.

Itching and rash can persist for 2 to 4 weeks after a successful permethrin treatment. This is because the body continues to react to the dead mites and their debris in the skin. Continued itching does not necessarily mean the treatment failed. Your doctor may recommend a topical corticosteroid to help manage post-treatment inflammation.

A second application is sometimes recommended 7 to 14 days after the first, particularly if symptoms persist or if the initial application was not applied correctly to all affected areas. Your physician will advise you based on your symptom status at follow-up.

Yes. Because scabies spreads through prolonged skin-to-skin contact, all household members and close contacts should be treated at the same time as the diagnosed individual, even if they have no symptoms yet. This prevents reinfestation.

Apply 5% permethrin cream thoroughly from the neck down to the soles of the feet, including under fingernails, between fingers and toes, and in skin folds. Leave it on for 8 to 14 hours, then wash off completely. Avoid contact with eyes and mucous membranes.

Permethrin is classified as FDA pregnancy category B, meaning animal studies have not shown fetal harm and it is generally considered one of the safer options for treating scabies during pregnancy. However, you should always discuss your full medical history with your physician before starting or refilling any medication during pregnancy or breastfeeding.

Doctronic uses an AI-powered evaluation to gather your medical history and symptom details. A licensed physician then reviews your information and, if appropriate, creates a personalized treatment plan including a prescription. The entire process is designed to be fast, safe, and convenient.

Yes. Doctronic operates with licensed physicians who review and approve all treatment plans. The platform is HIPAA-compliant, and all consultations are doctor-reviewed and audited to ensure patient safety. Doctronic is available to adults 18 and older in any U.S. state.