Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on December 21st, 2025.
Doxycycline is a versatile antibiotic used to treat various infections, including respiratory, skin, and sexually transmitted infections.
Dosage varies based on the condition being treated, age, and patient-specific factors.
Typical adult doses range from 100 mg once or twice daily, with adjustments for children and special conditions.
It is important to follow prescribed dosing schedules to avoid resistance and side effects.
If you have questions about your doxycycline dosage or need personalized advice, telehealth services like Doctronic.ai can connect you with licensed doctors 24/7.
Doxycycline is one of the most commonly prescribed antibiotics worldwide. Its effectiveness against a broad spectrum of bacterial infections makes it a go-to option for many healthcare providers. However, dosing doxycycline correctly is crucial to ensure the best outcomes and minimize side effects. This guide breaks down typical dosages, how to adjust doses for different conditions, and what to do if you miss a dose.
Form |
Strength |
Typical Adult Dose |
Typical Children’s Dose |
Frequency |
Route |
Maximum Daily Dose |
|---|---|---|---|---|---|---|
Tablet |
100 mg |
100 mg once or twice daily |
2.2 mg/kg every 12 hours (max 100 mg/dose) |
Once or Twice Daily |
Oral |
200 mg/day |
Capsule |
100 mg |
100 mg once or twice daily |
2.2 mg/kg every 12 hours |
Once or Twice Daily |
Oral |
200 mg/day |
Injection |
100 mg/mL |
100 mg every 12 hours |
Not typically used in children |
Twice Daily |
Intravenous |
200 mg/day |
For conditions like pneumonia or bronchitis, adults typically take 100 mg twice daily for 7 to 14 days. Children’s doses are weight-based, usually 2.2 mg per kilogram every 12 hours. Treatment length depends on severity and clinical response.
Doxycycline is often prescribed for moderate to severe acne. Adults usually take 50 to 100 mg once or twice daily. Treatment can last several weeks to months, but long-term use should be monitored by a healthcare provider.
For infections like chlamydia, a common regimen is 100 mg twice daily for 7 days. In some cases, a single dose may be recommended depending on the infection type and patient history.
Early Lyme disease treatment typically involves 100 mg twice daily for 10 to 21 days. Dosage adjustments may be necessary for severe or disseminated infections.
Adults generally take 100 mg orally once or twice daily. The exact dose depends on the type and severity of the infection. For example, mild infections may require just 100 mg once daily, while more serious infections often need 100 mg every 12 hours. Treatment duration varies but usually lasts between 7 and 14 days.
Dosing in children is weight-based, typically 2.2 mg/kg every 12 hours. The maximum dose per administration is usually capped at 100 mg. Doxycycline use in children under 8 years old is generally avoided unless the benefits outweigh the risks, due to potential effects on teeth and bone development.
If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double up to make up for a missed dose. Maintaining consistent levels of doxycycline in your system is important for effectiveness and to prevent antibiotic resistance.
Doxycycline is metabolized by the liver, so patients with liver impairment may require dose adjustments or closer monitoring. Consult your healthcare provider for personalized recommendations.
Because doxycycline is primarily eliminated via the gastrointestinal tract, dose adjustment is usually not necessary for patients with kidney disease. However, monitoring is advised in severe cases.
Taking too much doxycycline can cause nausea, vomiting, diarrhea, and photosensitivity. Severe overdose may lead to more serious complications, such as liver damage. Always follow prescribed dosages and seek immediate medical attention if an overdose is suspected.
Take doxycycline with a full glass of water to reduce irritation of the esophagus. Do not take doxycycline close to having dairy products.
Avoid lying down immediately after taking the medication to prevent esophageal ulcers.
Protect your skin from sunlight, as doxycycline can increase sensitivity to UV rays.
Complete the full course of treatment even if symptoms improve early.
Inform your doctor about any other medications or supplements you are taking to avoid interactions.
Personalized medical advice is key when it comes to antibiotics like doxycycline. If you have questions about your dosage, potential side effects, or need a second opinion, Doctronic.ai offers fast, convenient access to licensed doctors. Their AI-powered platform provides instant answers and 24/7 telehealth video visits, all for under $40. This approach ensures you get the most modern, personalized care without waiting days for an appointment.
Doxycycline remains a powerful tool against many infections, but correct dosing is essential for safety and effectiveness. Understanding how much to take, when, and for how long can make a big difference in your treatment outcome. Always consult a healthcare provider before starting or adjusting your dose. Doctronic.ai makes it easier than ever to get expert advice whenever you need it.
Yes, taking doxycycline with food can help reduce stomach upset, but avoid dairy products close to your dose as they can interfere with absorption.
Doxycycline is generally not recommended during pregnancy due to potential risks to the developing fetus. Always consult your doctor for alternatives.
Improvement in symptoms often occurs within a few days, but it is important to complete the full prescribed course to fully clear the infection.
Alcohol does not directly interfere with doxycycline, but it can impair immune function and increase side effects, so it is best to avoid or limit alcohol during treatment.
Common side effects include nausea, diarrhea, and photosensitivity. If side effects are severe or persistent, contact a healthcare provider promptly.
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