What is the Difference Between Lexapro and Generic Escitalopram?
Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.
Lexapro and FDA-approved generic escitalopram contain the same active ingredient and are expected to provide the same clinical benefits when used at equivalent doses. The primary differences lie in cost, appearance, and manufacturing. Generic escitalopram is often less expensive than brand-name Lexapro, although the amount saved depends on the pharmacy, insurance coverage, and available discounts. Lexapro and generic escitalopram are available in several strengths and forms, including 5 mg, 10 mg, and 20 mg tablets, and FDA-approved generics must meet FDA requirements for quality and bioequivalence. Generic versions may have different inactive ingredients like fillers or dyes, which can affect pill color or shape but not therapeutic action. Some patients report differences after switching formulations, although FDA-approved generics must meet established bioequivalence standards compared with the brand-name product.
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