Does Celexa Cause Less Weight Gain than Lexapro?
Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.
Yes, Celexa typically causes less weight gain than Lexapro based on clinical studies. Research shows that citalopram (Celexa) is associated with minimal weight changes, while escitalopram (Lexapro) can cause weight gain in 1-10% of patients during the first 6 months of treatment. Both medications are selective serotonin reuptake inhibitors (SSRIs), but they affect metabolism differently due to their distinct chemical structures. Individual responses vary significantly, with some patients experiencing no weight changes on either medication. Weight gain typically occurs gradually and ranges from 2-10 pounds when it does happen. Your healthcare provider can monitor your weight and adjust treatment if significant changes occur.
Still have questions about this?
Ask your AI DoctorKeep exploring
Related Questions
From the blog
More from Doctronic
Lexapro vs Celexa: Comparing Two Similar SSRIs
Lexapro and Celexa are both popular SSRI antidepressants that work similarly in the brain, but they have important differences in effectiveness, side…
How Long Does Celexa Stay in Your System? Missed Dose Guide
Celexa (citalopram) stays in your system for roughly 35 hours, which gives you a window to act if you miss a dose. Knowing exactly how long the…
Lexapro And Weight Gain: What to Expect
Lexapro (escitalopram) is one of the most prescribed antidepressants, but concerns about weight gain often worry patients. Understanding the real…