What Happens If You Accidentally Take Two Antidepressants?

Taking two antidepressants accidentally can cause dangerous drug interactions and serotonin syndrome. The severity depends on which medications you combined, the dosages, and your individual sensitivity. Serotonin syndrome affects up to 14% of patients taking multiple serotonergic drugs and can cause symptoms like fever, muscle rigidity, rapid heartbeat, and confusion. Some combinations like SSRIs with MAOIs are particularly risky and can be life-threatening. If you've accidentally double-dosed, contact your healthcare provider immediately or call poison control at 1-800-222-1222. Don't wait for symptoms to appear, as early intervention prevents serious complications.