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Mental Health

How Long Does It Take for Lexapro to Start Working?

Andre Stone | MD

Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.

Lexapro typically begins working within 1-2 weeks, though full effects may take 4-6 weeks to develop. Initial improvements in sleep, energy, and appetite often occur first, followed by gradual mood enhancement. Many patients experience meaningful symptom improvement within several weeks, but response rates and timing vary depending on the condition being treated and how improvement is defined. Some people notice subtle changes as early as the first week, while others may need up to 12 weeks for optimal results. Factors like dosage, individual metabolism, and severity of symptoms influence response time. If you don't notice improvement after 4-6 weeks, consult your healthcare provider about next steps. Contact your provider sooner if symptoms worsen or you develop unusual changes in mood or behavior, and seek urgent help for thoughts of self-harm or suicide.

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