Mental Health

Does Lexapro Cause Weight Gain?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 22nd, 2026.

Lexapro can cause weight gain, though it affects people differently. Clinical studies show that approximately 5-10% of patients experience significant weight gain (5+ pounds) while taking this SSRI antidepressant. The medication can increase appetite and slow metabolism in some individuals. Weight changes typically occur within the first few months of treatment, with an average gain of 2-10 pounds reported in long-term studies. Factors like dosage, individual metabolism, diet, and exercise habits influence whether weight gain occurs. If you're concerned about weight changes while taking Lexapro, discuss alternatives or management strategies with your healthcare provider.

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