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Off-Label Anxiety Treatment Options
March 31st, 2026

Does Gabapentin Help with Anxiety Attacks?

Gabapentin is not FDA-approved for anxiety attacks but is sometimes prescribed off-label for anxiety disorders. Originally developed as an anti-seizure medication, gabapentin affects GABA neurotransmitters in the brain, which can have calming effects. Studies suggest it may help reduce anxiety symptoms in about 60-70% of patients when used off-label. However, gabapentin carries risks including drowsiness, dizziness, and potential for dependence. The medication typically takes 1-2 weeks to show anxiety benefits. FDA-approved treatments like SSRIs, benzodiazepines, or therapy remain first-line options for panic attacks and anxiety disorders.

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