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Ehlers-Danlos Syndrome (EDS) is a group of hereditary disorders that affect connective tissue, which provides structure and support to the skin, joints, blood vessels, and organs. There are 13 recognized subtypes, with hypermobile EDS (hEDS) being the most common. Symptoms vary by subtype but often include joint hypermobility, chronic pain, skin that is unusually stretchy or fragile, and fatigue.

Most EDS subtypes are caused by mutations in genes that encode collagen or collagen-processing proteins. Collagen is a key structural protein found throughout the body. In hypermobile EDS, the exact genetic cause has not yet been identified. EDS is often inherited in an autosomal dominant or autosomal recessive pattern, depending on the subtype.

Common symptoms include joints that move beyond their normal range (hypermobility), frequent joint dislocations or subluxations, chronic musculoskeletal pain, fatigue, soft or velvety skin that may bruise easily, slow wound healing, and in some subtypes, fragile blood vessels. Many patients also experience autonomic dysfunction, digestive issues, and anxiety.

Diagnosis is primarily clinical, based on a thorough review of symptoms, personal and family history, and physical examination findings such as the Beighton score for hypermobility. Genetic testing can confirm specific subtypes such as classical or vascular EDS. Hypermobile EDS currently has no confirmatory genetic test and is diagnosed by clinical criteria.

There is currently no cure for EDS. Treatment focuses on managing symptoms, preventing injuries, and improving quality of life. Physical therapy, pain management, joint protection strategies, and treating specific complications are the mainstays of care. Some patients benefit from medications to address pain, muscle spasms, or autonomic symptoms.

Yes. Vascular EDS (vEDS) is one of the most serious subtypes and is caused by mutations in the COL3A1 gene. It can lead to spontaneous rupture of arteries, the bowel, or the uterus, and requires close medical monitoring. If vascular EDS is suspected, urgent specialist evaluation is recommended and certain activities may need to be restricted.

Doctronic uses an AI-powered evaluation to gather detailed information about your symptoms and health history. That information is then reviewed by a licensed physician who develops a personalized treatment plan. The entire process is designed to be fast, thorough, and convenient so you can get expert medical support from anywhere.

Yes. Doctronic works exclusively with licensed physicians who are board-certified and credentialed. All consultations are HIPAA-compliant, and every treatment plan is doctor-reviewed. Our platform is designed to uphold the same standards of care you would expect in a traditional clinical setting.