Where to Inject Ozempic
Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20, 2026.
Ozempic should be injected in three FDA-approved areas: thigh, upper arm, or abdomen. Rotate injection sites weekly to prevent lipodystrophy, which affects up to 30% of patients who repeatedly use the same spot. Choose areas with sufficient subcutaneous fat, avoiding muscles, veins, and scar tissue. The abdomen works best for most people, staying 2 inches away from the belly button. The thigh offers the largest injection area, while the upper arm requires assistance from others. Clean the injection site with alcohol, inject at a 90-degree angle, and hold for 6 seconds before withdrawing.
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