How Does Wegovy Work
Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.
Wegovy works by mimicking GLP-1, a natural hormone that regulates appetite and blood sugar levels. This FDA-approved weight loss medication slows gastric emptying, making you feel full longer after eating. It also directly affects your brain's appetite control centers, reducing food cravings by up to 15% in clinical trials. Participants in studies lost an average of 12-15% of their body weight over 68 weeks when combined with lifestyle changes. The medication is injected once weekly and takes 4-5 weeks to reach therapeutic levels in your system.
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