GLP 1 & Weight Loss

Is Zepbound the Same as Ozempic

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

No, Zepbound and Ozempic are different medications with different active ingredients and FDA approvals. Ozempic contains semaglutide and is approved for Type 2 diabetes management. Zepbound contains tirzepatide and received FDA approval in November 2023 exclusively for chronic weight management in adults with obesity or overweight conditions. While both are GLP-1 receptor agonists that can affect weight, they have distinct formulations, mechanisms of action, and intended medical uses. The key difference lies in their active ingredients and specific therapeutic indications.

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