Is Doxycycline Safe During Pregnancy?

No, doxycycline is not safe during pregnancy and is classified as FDA Pregnancy Category D. This antibiotic crosses the placenta and can cause permanent tooth discoloration, enamel defects, and impaired bone growth in developing babies. Studies show doxycycline use after the 4th month of pregnancy can lead to yellow-gray tooth staining in 58% of exposed children. The drug can also cause maternal liver toxicity and potentially contribute to birth defects. Healthcare providers typically prescribe safer alternatives like amoxicillin, cephalexin, or azithromycin for pregnant women who need antibiotic treatment.