Pregnancy & Medication Safety

Can You Use Hydrocortisone Cream While Pregnant?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

Yes, hydrocortisone cream is generally safe to use during pregnancy when applied topically. Topical hydrocortisone is classified as a Category C medication by the FDA, meaning studies haven't shown significant risk to the fetus. The American College of Obstetricians and Gynecologists considers low-potency topical corticosteroids like hydrocortisone safe for pregnant women when used appropriately. Only minimal amounts are absorbed through the skin, reducing systemic exposure to the developing baby. However, avoid using it on large areas of skin or for extended periods without medical supervision. Always consult your healthcare provider before starting any new medication during pregnancy, even over-the-counter treatments, to ensure it's appropriate for your specific situation.

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