Can You Take Benadryl While Pregnant?

Benadryl (diphenhydramine) is generally considered safe during pregnancy when used occasionally. The FDA classifies it as a Category B medication, meaning animal studies show no fetal risk, though human studies are limited. Most healthcare providers approve short-term use for allergies, nausea, or sleep issues during pregnancy. However, regular or high-dose use should be avoided, especially in the third trimester, as it may cause complications like low birth weight or premature labor. Studies indicate that up to 14% of pregnant women use antihistamines like Benadryl. Always consult your healthcare provider before taking any medication during pregnancy to ensure it's appropriate for your specific situation and stage of pregnancy.