GLP 1 & Weight Loss

How Much Weight Can You Lose on Ozempic

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

Most patients lose 15-20% of their body weight on Ozempic over 68 weeks of treatment. Clinical trials show average weight loss of 14.9% at the highest dose (2.4mg), with some individuals losing up to 30% of their starting weight. Your results depend on starting weight, diet adherence, exercise routine, and dosage progression. Most significant weight loss occurs in the first 6-12 months, with gradual tapering afterward. Individual results vary based on metabolism, lifestyle factors, and adherence to treatment protocols.

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