How Long Does Nausea Last with Ozempic

Yes, Ozempic can cause nausea that typically lasts 4-8 weeks as your body adjusts to the medication. Most patients experience the strongest nausea during the first 2-4 weeks, with symptoms gradually improving as they continue treatment. Studies show that up to 44% of patients report nausea when starting Ozempic, but only 5-15% discontinue due to persistent symptoms. The nausea often correlates with dose increases and tends to be most noticeable 1-3 days after each injection. We recommend starting with smaller meals, avoiding fatty foods, and taking your injection at the same time weekly to minimize side effects.