How Long Do Semaglutide Side Effects Last

Semaglutide side effects typically last 2-8 weeks as your body adjusts to the medication. Most gastrointestinal symptoms like nausea, vomiting, and diarrhea peak during the first 4 weeks and gradually diminish as you maintain a stable dose. Clinical trials show that 85% of patients experience reduced nausea by week 8 of treatment. The severity and duration depend on your starting dose, how quickly it's increased, and individual tolerance. Common side effects include stomach upset, decreased appetite, and occasional headaches. If side effects persist beyond 8 weeks or become severe, consult your healthcare provider about dose adjustments or alternative treatment options.