How Long After Starting Wegovy Do You Lose Your Appetite?

Wegovy typically reduces appetite within the first 1-2 weeks of starting treatment, though some patients notice changes as early as 3-5 days. The medication's active ingredient, semaglutide, works by mimicking GLP-1 hormones that signal fullness to your brain and slow gastric emptying. Clinical studies show that 85% of patients experience significant appetite suppression by week 4. The effect builds gradually as your dose increases during the titration schedule - you'll start with 0.25mg weekly and increase every 4 weeks until reaching the maintenance dose of 2.4mg. Individual responses vary based on factors like metabolism, starting weight, and adherence to dosing.