Does Ozempic Cause Constipation

Yes, Ozempic commonly causes constipation in approximately 20% of patients taking this medication. Constipation occurs because semaglutide, the active ingredient in Ozempic, slows gastric emptying and reduces intestinal motility as part of its mechanism to control blood sugar and promote weight loss. This side effect typically emerges within the first few weeks of treatment and may persist throughout therapy. Most patients experience mild to moderate constipation that can be managed with increased fiber intake, adequate hydration, and regular physical activity. We recommend discussing persistent or severe constipation with your healthcare provider, as they may suggest dose adjustments or additional treatments to help manage this common but manageable side effect.