GLP 1 & Weight Loss

Does Ozempic Affect Your Immune System?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 22nd, 2026.

Yes, Ozempic can affect your immune system, though the effects are generally mild. The medication may slightly suppress certain immune responses, which could theoretically increase infection risk. Clinical trials showed upper respiratory tract infections occurred in 8-10% of patients taking semaglutide compared to 6% taking placebo. However, these effects are typically temporary and resolve as your body adjusts to the medication. Most patients experience no significant immune-related issues while taking Ozempic. If you're considering GLP-1 medications, we can help you understand potential side effects and determine if Ozempic is right for your health profile through a personalized consultation.

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