GLP 1 & Weight Loss

Does Ozempic Affect Your Blood Pressure?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.

Yes, Ozempic can affect your blood pressure by lowering it in most patients. Semaglutide, Ozempic's active ingredient, typically reduces systolic blood pressure by 2-6 mmHg through weight loss and improved insulin sensitivity. Clinical trials show that 60-70% of patients experience measurable blood pressure reductions within 12-16 weeks of treatment. However, some patients may initially experience slight blood pressure fluctuations as their body adjusts to the medication. If you're taking blood pressure medications alongside Ozempic, your doctor may need to adjust dosages to prevent hypotension. Monitor your blood pressure regularly during the first few months of treatment to track these changes.

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