Does Mounjaro Affect Your Gallbladder?

Yes, Mounjaro can affect your gallbladder and may increase the risk of gallbladder problems. Clinical trials showed that GLP-1 receptor agonists like Mounjaro are associated with a higher incidence of gallbladder disorders, including gallstones and cholecystitis. About 1-2% of GLP-1 users experience gallbladder events. The risks are greater with higher doses and greater weight loss. The medication slows gallbladder emptying and can affect bile flow, potentially leading to bile stasis and stone formation. Studies indicate that rapid weight loss (more than 3 pounds per week) further elevates gallbladder risks. If you experience severe abdominal pain, nausea, or yellowing of skin while taking Mounjaro, seek immediate medical attention.