Pregnancy & Medication Safety

Can You Take Zyrtec During Pregnancy?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 20th, 2026.

Yes, Zyrtec (cetirizine) is generally considered safe to take during pregnancy. The FDA classifies cetirizine as a Category B medication, meaning animal studies have not shown fetal harm and no adequate human studies exist. Multiple observational studies involving over 10,000 pregnant women have found no increased risk of birth defects when taking cetirizine during pregnancy. However, like all medications during pregnancy, it should only be used when the benefits outweigh potential risks. Most doctors recommend taking the lowest effective dose and consulting with your healthcare provider before starting any new medication during pregnancy, especially during the first trimester when organ development occurs.

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