GLP 1 & Weight Loss

Can You Take Magnesium While on Semaglutide?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.

Yes, you can safely take magnesium supplements while on semaglutide. There are no known drug interactions between magnesium and GLP-1 medications like semaglutide, Ozempic, or Wegovy. Magnesium may actually help counteract some common semaglutide side effects, as studies show up to 50% of users experience digestive issues like constipation. Magnesium supports muscle function, nerve health, and digestive regularity - benefits that complement your weight loss journey. Research indicates that maintaining adequate magnesium levels (320-420mg daily for adults) supports metabolic health and may enhance treatment outcomes. Consult with your healthcare provider to determine the right magnesium dosage for your specific needs and current medications.

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