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Zanaflex (tizanidine) is a prescription muscle relaxant approved to manage muscle spasticity. It is commonly used for spasticity related to multiple sclerosis, spinal cord injury, or other conditions that affect the central nervous system and cause involuntary muscle tightening or spasms.

Tizanidine is a central alpha-2 adrenergic agonist. It works by binding to receptors in the spinal cord that inhibit the release of excitatory amino acids, reducing overactive nerve signals that cause muscles to spasm or stiffen involuntarily.

Tizanidine is a short-acting medication. Peak effects typically occur within one to two hours of taking a dose, and the duration of action is generally three to six hours, making it well suited for managing spasticity during specific activities.

Common side effects include drowsiness, dizziness, dry mouth, weakness, and low blood pressure. Because sedation can be significant, patients are generally advised to avoid driving or operating heavy machinery until they know how the medication affects them.

Tizanidine has important drug interactions. It should not be taken with fluvoxamine or ciprofloxacin, as these can substantially increase tizanidine blood levels. It can also enhance the blood-pressure-lowering effect of other antihypertensive medications. Always share your full medication list with your physician.

Abrupt discontinuation of tizanidine, especially at higher doses or after prolonged use, can cause rebound hypertension, tachycardia, and increased spasticity. Your physician will advise tapering the dose gradually when discontinuing the medication.

Doctronic uses an AI-guided evaluation to gather your symptoms, medical history, and relevant details. A licensed physician then reviews your information, makes a clinical determination, and creates a personalized treatment plan, all without requiring an in-person visit.

Yes. Doctronic connects you with fully licensed physicians whose work is doctor-reviewed and regularly audited for quality and safety. The platform is HIPAA-compliant, and prescriptions are only issued when clinically appropriate for your situation.