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Mytesi (crofelemer) is FDA-approved to relieve non-infectious diarrhea in adults living with HIV/AIDS who are on antiretroviral therapy. It is not intended to treat diarrhea caused by infections.

Mytesi works by blocking two chloride ion channels in the intestinal lining. By reducing the flow of chloride and water into the gut, it decreases the volume and frequency of loose stools without being significantly absorbed into the bloodstream.

Mytesi is taken as a 125 mg delayed-release tablet twice daily, with or without food. You should swallow the tablet whole and not crush or chew it.

The most commonly reported side effects include upper respiratory tract infections, bronchitis, cough, flatulence, and nausea. Because Mytesi acts locally in the gut and has minimal systemic absorption, systemic side effects are generally uncommon.

Mytesi has minimal systemic absorption and has not shown clinically significant interactions with most antiretroviral drugs in clinical studies. However, your physician will review your full medication list to ensure safety before prescribing.

Some patients notice improvement within the first week of treatment, but individual responses vary. Your physician may assess your response over several weeks to determine whether Mytesi is providing adequate relief.

Doctronic uses an AI-powered evaluation to gather your symptoms and medical history, which is then reviewed by a licensed physician. If appropriate, the physician creates a personalized treatment plan, which may include a prescription sent directly to your pharmacy.

Yes. All evaluations are conducted and reviewed by licensed, board-eligible physicians. Doctronic is HIPAA-compliant and every treatment decision is doctor-reviewed and audited to meet the highest standards of patient safety.