Dupixent Dosage Guide: How Much to Take and When (With Chart)

Alan Lucks | MD

Medically reviewed by Alan Lucks | MD, Alan Lucks MDPC Private Practice - New York on January 2nd, 2026.

Key Takeaways

  • Dupixent (dupilumab) is a biologic medication used to treat several inflammatory conditions, including eczema, asthma, and nasal polyps.
  • Dosage varies by condition, age, and patient weight, with specific loading and maintenance doses.
  • Dupixent is administered by subcutaneous injection, typically every two weeks.
  • Adjustments may be necessary for specific medical conditions or based on patient response.
  • Missed doses should be taken as soon as remembered, unless close to the next dose.
  • For personalized guidance and telehealth consultations on Dupixent dosage, Doctronic.ai offers expert AI-powered, doctor-supported care.

Understanding Dupixent Uses and Dosages

Dupixent, known generically as dupilumab, has become a vital treatment option for people suffering from moderate-to-severe atopic dermatitis (eczema), asthma, and chronic rhinosinusitis with nasal polyps. As a biologic therapy, it targets specific pathways in the immune system to reduce inflammation. Because Dupixent is a prescription medication administered via injection, understanding the correct dosage and schedule is essential for safety and effectiveness.

Below is a detailed guide to Dupixent dosage, including a chart for quick reference, information on dosing by condition, and tips on what to do if you miss a dose. If you want personalized advice or have questions about your treatment, Doctronic.ai provides fast, reliable telehealth visits with licensed doctors who can tailor dosage guidance to your unique needs.

Dupixent Dosage Chart

Form

Strength

Typical Adult Dose

Typical Children’s Dose

Frequency

Route

Maximum Daily Dose

Injection

300 mg/2 mL prefilled syringe or pen

Initial loading dose: 600 mg (two 300 mg injections)  Maintenance: 300 mg every 2 weeks

Weight-based dosing for children 6 years and older (see below)

Every 2 weeks

Subcutaneous

600 mg loading dose, then 300 mg biweekly

Dupixent Dosage by Condition

Atopic Dermatitis (Eczema)

For adults and adolescents 12 years and older with moderate-to-severe atopic dermatitis, the usual starting dose is a loading dose of 600 mg (two injections of 300 mg each). After this, a maintenance dose of 300 mg is given every two weeks. For children aged 6 to 11 years, dosing is weight-based:

  • 15 to less than 30 kg: 300 mg every 4 weeks

  • 30 kg or more: 300 mg every 2 weeks

Asthma

Adults and adolescents 12 years and older with moderate-to-severe eosinophilic or oral corticosteroid-dependent asthma typically receive a loading dose of 400 mg (two 200 mg injections) or 600 mg (two 300 mg injections), as determined by physician assessment. Maintenance dosing is 200 mg or 300 mg every two weeks. The exact dose depends on the severity and patient weight.

Chronic Rhinosinusitis with Nasal Polyps

The recommended dose for adults is a loading dose of 600 mg followed by 300 mg every two weeks. This dosing helps reduce nasal polyp size and improve nasal airflow.

What is the Typical Dupixent Dose for Adults?

Most adult patients start with a loading dose of 600 mg (two injections of 300 mg) to quickly build up medication levels in the body. Maintenance doses are then administered every two weeks at 300 mg. Some patients with asthma may receive 200 mg doses instead, based on their doctor’s evaluation.

Dupixent is injected under the skin, usually in the thigh, abdomen, or upper arm. Patients or caregivers are often trained to self-inject at home, making treatment convenient and less disruptive.

What is the Typical Dupixent Dose for Children?

Children aged 6 to 11 years receive weight-based dosing. Those weighing between 15 and 30 kg typically get 300 mg every four weeks, while children over 30 kg follow the adult dosing schedule of 300 mg every two weeks. Dupixent is not approved for children under 6 years old.

What to Do If You Miss a Dose of Dupixent?

If a dose is missed, take it as soon as you remember unless the next scheduled dose is within 7 days. In that case, skip the missed dose and resume your regular dosing schedule. Do not double up doses to catch up. If unsure, contact your healthcare provider or use Doctronic.ai to get quick advice from a medical professional.

How to Adjust Your Dupixent Dose for Certain Medical Conditions

Kidney or Liver Issues

Currently, no specific dose adjustments are recommended for patients with mild to moderate kidney or liver impairment. However, patients with severe organ dysfunction should consult their healthcare provider before starting Dupixent.

Other Immune Conditions

Because Dupixent affects the immune system, patients with other immune-related conditions or infections should discuss risks and benefits with their doctors. Dose adjustments may be necessary based on individual health status.

Dupixent Overdose and Warnings

There is limited data on Dupixent overdose, but taking more than the prescribed dose is not advised. Overdose symptoms could include increased side effects such as injection site reactions, eye inflammation, or allergic reactions. Seek immediate medical attention if an overdose is suspected.

Patients should inform their healthcare providers about all medications and supplements they are taking, as Dupixent may interact with other treatments. Regular monitoring is essential to ensure safety and effectiveness.

Tips for Taking Dupixent Safely

  • Follow the prescribed dosing schedule carefully.

  • Store Dupixent in the refrigerator and protect it from light.

  • Do not shake the injection pen or syringe.

  • Rotate injection sites to avoid irritation.

  • Report any side effects or unusual symptoms to your healthcare provider promptly.

  • Use telehealth services like Doctronic.ai to get expert advice without leaving home.

Learn More About Dupixent Dosage With Doctronic

Getting the proper Dupixent dosage can be complex, especially when factoring in your medical history, weight, and condition severity. Doctronic.ai offers a unique AI-powered platform combined with access to licensed doctors who understand the latest in modern medicine. You can get personalized dosage recommendations, answers to your questions, and even schedule telehealth visits-all from the comfort of your home.

With over 10 million users, Doctronic is revolutionizing healthcare by providing fast, smart, and personal care. Visit Doctronic.ai today to learn more about Dupixent and how to manage your treatment effectively.

Woman smiling while giving herself a subcutaneous injection in the abdomen

Frequently Asked Questions

No. Dosage changes should only be made under the guidance of a healthcare professional to ensure safety and effectiveness.

Dupixent is given as a subcutaneous injection every two weeks, usually in the thigh, abdomen, or upper arm.

Common side effects include injection site reactions, cold sores, and eye inflammation. Contact your doctor if side effects are severe or persistent.

Dupixent is approved for children aged 6 years and older with specific dosing based on weight. Consult your pediatrician for personalized advice.

Doctronic.ai offers AI-powered and doctor-supported telehealth visits to answer your questions and provide personalized dosage guidance quickly and conveniently.

References

The Bottom Line

Dupixent is a powerful treatment that can significantly improve the quality of life for patients with certain inflammatory diseases. However, correct dosing is key to maximizing benefits and minimizing risks. Always follow your healthcare provider’s instructions and consult them if you experience any issues or have questions about your dosage.

For those seeking convenient, expert advice on Dupixent dosing and other health concerns, Doctronic.ai is an excellent resource. It combines AI precision with human empathy, ensuring you get the best care possible without delays.

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