Step-by-Step: How to Evaluate Primary Amenorrhea
Published: May 26, 2024
Evaluating primary amenorrhea can be complex. Follow this step-by-step guide to understand the essential diagnostic procedures.
Contents
Initial Assessment
The first step is a thorough medical history and physical examination. Look for signs of pubertal development and any abnormalities in internal reproductive structures. These observations guide further diagnostic testing.
Hormonal Testing
Hormonal tests, like measuring follicle-stimulating hormone (FSH), help determine if the cause is central or ovarian. Elevated FSH might suggest ovarian insufficiency, while low levels could indicate central causes.

Imaging and Genetic Testing
If initial tests are inconclusive, imaging studies like ultrasound or MRI can visualize internal structures. Genetic testing may be necessary for conditions like Turner syndrome or gonadal dysgenesis.
Frequently Asked Questions
Conduct a detailed medical history and physical exam.
They help identify if the cause is central or ovarian.
Imaging is used when initial tests are inconclusive.
Key Takeaways
A systematic approach to evaluation ensures accurate diagnosis of primary amenorrhea.
Start your evaluation journey with Doctronic and get expert guidance on primary amenorrhea.Related Articles
References
Zhong Q, Layman LC. Fertil Steril 2012; 98:775.
Quaynor SD, Stradtman EW Jr, Kim HG, et al. N Engl J Med 2013; 369:164.
Always discuss health information with your healthcare provider.