Sleep

Does Trazodone Cause Next-Day Drowsiness?

Linda Girgis | MD

Medically reviewed by Linda Girgis | MD, Girgis Family Medicine on August 21st, 2026.

Yes, trazodone frequently causes next-day drowsiness, particularly at higher doses. This sedating effect occurs because trazodone has a half-life of 5-9 hours, meaning it can remain active in your system well into the following day. Studies show that 15-20% of patients experience significant morning grogginess when taking doses above 150mg. The drowsiness typically peaks 1-3 hours after taking the medication and gradually diminishes throughout the day. Taking trazodone earlier in the evening, around 1-2 hours before your intended bedtime, can help minimize morning sedation while maintaining its sleep-promoting benefits.

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