Does Botox Actually Help with Chronic Migraines?
Medically reviewed by Andre Stone | MD, University of Pittsburgh School of Medicine on August 25th, 2026.
Yes, Botox is FDA-approved and clinically proven to prevent chronic migraines in adults. A trained clinician typically gives 31 injections across specific areas of the head and neck every 12 weeks. Side effects can include neck pain, muscle weakness, and eyelid drooping; patients should discuss the treatment’s risks and suitability with their clinician. In clinical trials, people receiving Botox had about 8-9 fewer headache days per month than they had before treatment, although people receiving placebo injections also improved. Individual results vary. The medication works by blocking nerve signals that trigger pain pathways associated with migraines. Some people improve after the first treatment, while others may not see a meaningful benefit until the second or third treatment cycle. Not everyone responds.
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