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You apply one Xulane patch to clean, dry skin on your abdomen, buttocks, back, or upper arm at the start of your cycle. You wear it for seven days, then replace it with a new patch for two more weeks, and remove all patches during the fourth week before starting a new cycle. Each patch should be pressed firmly in place for at least 10 seconds.

When used correctly and consistently, Xulane is more than 99% effective at preventing pregnancy. With typical use, effectiveness is estimated at around 91%, similar to daily oral contraceptives. Effectiveness may be reduced in people weighing more than 198 pounds (90 kg).

Common side effects include skin irritation or redness at the patch site, breast tenderness or discomfort, headache, nausea, and mood changes. Breakthrough bleeding or spotting may also occur, particularly in the first few cycles.

Yes. Like all combined hormonal contraceptives, Xulane carries a small increased risk of blood clots, stroke, and heart attack. This risk is higher in people who smoke, are over 35, or have a personal or family history of clotting disorders. Your physician will review your health history to determine whether Xulane is safe for you.

Yes. Studies have shown that Xulane exposes users to approximately 60% more total estrogen (as measured by area under the curve) compared to a 35 microgram ethinyl estradiol oral contraceptive. Your physician will take this into account when evaluating whether Xulane is the right choice for you.

If a patch detaches partially or fully for less than 24 hours, try to reapply it or apply a new patch immediately. If it has been off for more than 24 hours or you are unsure how long it has been detached, apply a new patch and use a backup non-hormonal contraceptive method for at least seven days. Do not use tape or bandages to reattach a loose patch.

Doctronic uses an AI-guided evaluation to gather your medical history and symptoms, which is then reviewed by a licensed physician. If a prescription is appropriate, the physician creates a personalized treatment plan. The entire process happens online, making care accessible without an in-person visit.

Yes. Doctronic works exclusively with licensed physicians who review and are accountable for every patient evaluation. The platform is HIPAA-compliant, and all clinical decisions are doctor-reviewed and audited to ensure your safety and the quality of your care.