Get Ponstel Online

Ponstel (mefenamic acid) is a prescription NSAID approved for the relief of moderate to severe pain associated with primary dysmenorrhea (menstrual cramps) in adults. It is generally used for short periods, typically no more than 2 to 3 days per menstrual cycle.

Ponstel works by inhibiting cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins. Prostaglandins are hormone-like substances that cause the uterus to contract forcefully during menstruation, leading to cramping and pain. By lowering prostaglandin levels, Ponstel helps relax uterine contractions and ease discomfort.

Ponstel is most effective when started at the onset of menstrual bleeding or at the first sign of cramping. Your physician will determine the appropriate dose and duration, which is typically 500 mg as a starting dose followed by 250 mg every 6 hours for up to 3 days.

The most commonly reported side effects include stomach upset, nausea, diarrhea, and abdominal pain. Like all NSAIDs, Ponstel carries a risk of more serious gastrointestinal, cardiovascular, and renal effects, especially with prolonged use. Your physician will review your history to ensure Ponstel is safe for you.

Ponstel should not be used by people with a history of peptic ulcers, significant kidney or liver impairment, heart failure, known NSAID or aspirin hypersensitivity, or those in the third trimester of pregnancy. It should also be avoided in patients who have had bypass (CABG) surgery. Your Doctronic physician will screen for these contraindications before prescribing.

Ponstel can interact with blood thinners such as warfarin, other NSAIDs, aspirin, certain blood pressure medications (including ACE inhibitors and ARBs), diuretics, and lithium, among others. Always disclose all medications and supplements you take during your Doctronic evaluation so your physician can check for interactions.

Doctronic uses an AI-guided evaluation to gather your symptoms, medical history, and relevant details. A licensed physician then reviews your information, determines whether treatment is appropriate, and creates a personalized treatment plan, which may include a prescription sent to your preferred pharmacy.

Yes. Doctronic connects you with real, licensed physicians who review and approve all treatment decisions. Every case is doctor-reviewed and audited for quality, and the platform is fully HIPAA-compliant to protect your health information. Doctronic is available to adults 18 and older in any U.S. state.