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Actigall (ursodiol) is a naturally occurring bile acid that reduces the amount of cholesterol the liver secretes into bile. When bile contains less cholesterol relative to bile acids, it becomes less saturated, and existing cholesterol gallstones can gradually dissolve over months of treatment. It works best on small, non-calcified cholesterol stones.

Stone dissolution is a slow process. Most patients require 6 to 24 months of continuous therapy. Smaller stones generally dissolve faster than larger ones. Your physician will recommend periodic ultrasound monitoring to track progress and adjust treatment as needed.

No. Actigall is effective only against cholesterol gallstones that are not calcified (hardened with calcium). It does not dissolve pigment stones or stones with significant calcium content. Imaging is important to confirm stone type before starting therapy.

Good candidates include adults with small to medium non-calcified cholesterol gallstones who want to avoid surgery, patients with a functioning gallbladder, and individuals at high risk for gallstone formation during rapid weight loss. People with calcified stones, bile duct obstruction, or severe liver disease are generally not candidates.

Actigall is generally well tolerated. The most commonly reported side effects include diarrhea, constipation, nausea, upset stomach, and back pain. Serious side effects are uncommon but your physician will monitor your liver function periodically during treatment.

Gallstones may recur after stopping Actigall. Studies show that stones return in a significant proportion of patients within a few years of discontinuing therapy. Your physician may recommend long-term or maintenance dosing in certain situations to reduce the risk of recurrence.

Doctronic uses an AI-guided evaluation to collect a detailed picture of your symptoms, medical history, and relevant imaging or test results. A licensed physician then reviews your information, makes an independent clinical assessment, and creates a personalized treatment plan, which may include a prescription if appropriate.

Yes. Doctronic connects you with fully licensed physicians who independently review every case. All consultations are doctor-reviewed and audited for quality, and the platform is HIPAA-compliant to protect your personal health information. Care is available to adults 18 and older in any U.S. state.