Get Actigall Online

Actigall (ursodiol) is a prescription bile acid used to dissolve cholesterol gallstones and prevent new ones from forming. Get a physician evaluation and prescription online, without leaving home.

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Medications We Prescribe for Gallstone Disease

Actigall

Ursodiol

The primary formulary treatment for cholesterol gallstone dissolution and prevention. Taken orally, typically twice daily, it reduces bile cholesterol saturation to dissolve existing stones and prevent new ones.

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Questran

Cholestyramine

A bile acid sequestrant sometimes used adjunctively to manage bile acid-related symptoms such as bile acid diarrhea or pruritus associated with biliary disease.

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Nexium

Esomeprazole

A proton pump inhibitor used to manage dyspepsia, acid reflux, and upper GI discomfort that commonly accompanies gallstone disease or follows biliary events.

Get Nexium online Drug Info

Metamucil

Psyllium

A soluble fiber supplement that may help reduce bile cholesterol levels and support digestive regularity, used as a complementary measure alongside primary gallstone therapy.

Get Metamucil online Drug Info

Pricing that won't make you sick

Chat for free, see an online doctor for $39/visit, or renew a prescription online for as low as $0

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These are stories from real users who turned to Doctronic for answers when it mattered most.

  • Preparing for a doctor visit
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  • Understanding a diagnosis
  • Managing chronic illness
  • Navigating healthcare
  • A second opinion
  • Improving health

How Gallstone Disease Treatment Works at Doctronic


Start a Free Chat With Doctronic

Doctronic answers your health questions with personalized medical insights and helps our doctors create a better treatment plan for you.


Meet With a Licensed Doctor For Treatment

Book a $39 telehealth appointment (or copay), with an average wait of about 5 minutes. Our doctors create personalized treatment plans with prescriptions when needed.


Pick Up Your Prescription

Our doctors prescribe non-controlled medications in all 50 states and send prescriptions to your pharmacy for same-day pickup.

Hear from our users

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What Is Actigall?

Actigall (ursodiol) is a prescription medication used to manage cholesterol gallstone disease, including dissolution of existing gallstones and prevention of gallstone formation in patients undergoing rapid weight loss. It works by reducing the amount of cholesterol secreted by the liver into bile, decreasing bile saturation and allowing cholesterol stones to slowly dissolve. With the right dose and ongoing monitoring, most patients with small, non-calcified cholesterol gallstones can achieve meaningful stone reduction or prevention of new stone development.

  • Dissolves small cholesterol gallstones and prevents new stone formation
  • Get personalized guidance from doctor-trained AI
  • Explore treatment and prescription options

Is Online Actigall Treatment Right for You?

Actigall (ursodiol) is appropriate for adults with cholesterol gallstone disease, particularly those with small to medium, non-calcified cholesterol stones who are not candidates for surgery, or those at high risk of gallstone formation during rapid weight loss programs. Your Doctronic physician will review your imaging history, stone characteristics, and overall health to determine whether ursodiol is the right treatment for you.

Because Actigall acts on the biliary system, your physician will also evaluate your liver function and any history of biliary tract disorders, including bile duct obstruction, cholangitis, or significant liver disease, as these conditions may affect candidacy for treatment.

  • Diagnosed with cholesterol gallstone disease or gallstone prevention need
  • Get personalized guidance from AI and clinicians
  • Explore treatment and prescription refill options
  • Access care from home, often the same day
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Diagnosed with cholesterol gallstones or biliary disease Ultrasound confirming small, non-calcified cholesterol stones Experiencing right upper quadrant discomfort or biliary colic Need a prescription refill Adults 18+ in any U.S. state

Frequently asked questions

Actigall (ursodiol) is a naturally occurring bile acid that reduces the amount of cholesterol the liver secretes into bile. When bile contains less cholesterol relative to bile acids, it becomes less saturated, and existing cholesterol gallstones can gradually dissolve over months of treatment. It works best on small, non-calcified cholesterol stones.

Stone dissolution is a slow process. Most patients require 6 to 24 months of continuous therapy. Smaller stones generally dissolve faster than larger ones. Your physician will recommend periodic ultrasound monitoring to track progress and adjust treatment as needed.

No. Actigall is effective only against cholesterol gallstones that are not calcified (hardened with calcium). It does not dissolve pigment stones or stones with significant calcium content. Imaging is important to confirm stone type before starting therapy.

Good candidates include adults with small to medium non-calcified cholesterol gallstones who want to avoid surgery, patients with a functioning gallbladder, and individuals at high risk for gallstone formation during rapid weight loss. People with calcified stones, bile duct obstruction, or severe liver disease are generally not candidates.

Actigall is generally well tolerated. The most commonly reported side effects include diarrhea, constipation, nausea, upset stomach, and back pain. Serious side effects are uncommon but your physician will monitor your liver function periodically during treatment.

Gallstones may recur after stopping Actigall. Studies show that stones return in a significant proportion of patients within a few years of discontinuing therapy. Your physician may recommend long-term or maintenance dosing in certain situations to reduce the risk of recurrence.

Doctronic uses an AI-guided evaluation to collect a detailed picture of your symptoms, medical history, and relevant imaging or test results. A licensed physician then reviews your information, makes an independent clinical assessment, and creates a personalized treatment plan, which may include a prescription if appropriate.

Yes. Doctronic connects you with fully licensed physicians who independently review every case. All consultations are doctor-reviewed and audited for quality, and the platform is HIPAA-aligned to protect your personal health information. Care is available to adults 18 and older in any U.S. state.