Contents
The Lugano Classification: A New Standard for Lymphoma Staging
Published: Dec 27, 2023
The Lugano Classification is a modern system for staging lymphoma that helps doctors determine how far the cancer has spread. Understanding this system can help patients better grasp their diagnosis and treatment plan.
What is the Lugano Classification?
The Lugano Classification, introduced in 2014, is an updated version of the older Ann Arbor staging system. It incorporates modern imaging techniques, particularly PET scans, to more accurately stage both Hodgkin and non-Hodgkin lymphomas. This system helps doctors determine the extent of the disease and guide treatment decisions.
The Four Stages of Lymphoma
The Lugano Classification divides lymphoma into four stages. Stage I involves a single lymph node region or a single organ. Stage II involves two or more lymph node regions on the same side of the diaphragm. Stage III means the lymphoma is in lymph node regions or organs on both sides of the diaphragm. Stage IV indicates widespread involvement of one or more organs beyond the lymph system.
The Role of PET Scans
PET scans play a crucial role in the Lugano Classification. They help distinguish between limited and advanced disease more accurately than CT scans alone. PET scans are also used to assess response to treatment, using a five-point scale called the Deauville criteria. This helps doctors determine if treatment is working or if changes are needed.
Other Important Factors
The Lugano Classification also considers other factors beyond just stage. It notes whether the lymphoma is causing any symptoms (like fever or weight loss) and whether there are any large tumor masses (called bulky disease). However, unlike the older system, it doesn't use letters (A or B) to denote the presence or absence of symptoms, as this wasn't found to be consistently important for prognosis.
Frequently Asked Questions
It incorporates PET scans and simplifies some categories.
Not necessarily; other factors also influence prognosis and treatment.
Typically at diagnosis, during treatment, and to confirm remission.
Yes, it can change based on how the lymphoma responds to treatment.
It's used for most, but some rare types may use different systems.
Key Takeaways
The Lugano Classification provides a standardized way to assess lymphoma extent and treatment response, improving patient care.
References
- Cheson BD, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol 2014; 32:3059.
- Barrington SF, et al. Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group. J Clin Oncol 2014; 32:3048.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
AI Doctor Visit Required
Appointments available 24/7
Top licensed doctors
Available in all 50 states
Full service care
Prescriptions, referrals & treatment
No insurance needed
All notes available in Doctronic
15-min consultation. No hidden costs.
AI Doctor Visit Required
Please Chat With Our AI Doctor First
Our AI doctor assessment helps our human doctors prepare for your video visit and provide better care
For safety reasons we have been forced to end this consultation.
If you believe this is a medical emergency please call 911 or your local emergency services immediately.
If you are experiencing emotional distress, please call the the Suicide & Crisis Lifeline at 988 or your local crisis services immediately.
Contact us
You can also email us at help@doctronic.ai
We aim to reply within 5-7 days
How likely are you to recommend Doctronic to friends or family?