Bone Marrow Biopsy: What Lymphoma Patients Should Expect
Published: Sep 19, 2024
A bone marrow biopsy is an important procedure for many lymphoma patients. While it may sound intimidating, understanding what to expect can help ease anxiety and prepare you for this crucial test.
Contents
Why is a Bone Marrow Biopsy Needed?
Bone marrow biopsies help doctors determine if lymphoma has spread to the bone marrow. This information is crucial for accurate staging and treatment planning. It's also used to investigate unexplained blood count abnormalities or to confirm that a patient with apparent early-stage disease doesn't have more widespread involvement.
What Happens During the Procedure?
The biopsy is usually taken from the hip bone. After numbing the area, a special needle is inserted to collect a small sample of bone marrow. You may feel pressure or brief pain during the sample collection. The entire procedure typically takes about 20-30 minutes. While it can be uncomfortable, most patients find it tolerable.

After the Biopsy
After the procedure, you'll need to keep the biopsy site clean and dry for 24-48 hours. You may experience some soreness for a few days. Complications are rare but can include bleeding or infection. Your doctor will provide specific care instructions and signs to watch for.
Understanding the Results
Results are usually available within a few days to a week. The samples are examined under a microscope and may undergo additional tests like flow cytometry or genetic analysis. Your doctor will explain what the results mean for your diagnosis and treatment plan.
Frequently Asked Questions
Not always; it depends on the type of lymphoma and other factors.
Most patients experience brief discomfort, but not severe pain.
It's best to have someone drive you home afterward.
Most people can return to normal activities the next day.
It varies, but often just once for initial staging.
Key Takeaways
While a bone marrow biopsy can be daunting, it provides valuable information to guide your lymphoma treatment.
References
- Cheson BD, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol 2014; 32:3059.
- Adams HJ, et al. FDG PET/CT for the detection of bone marrow involvement in diffuse large B-cell lymphoma: systematic review and meta-analysis. Eur J Nucl Med Mol Imaging 2014; 41:565.
- Rutherford SC, et al. Relevance of Bone Marrow Biopsies for Response Assessment in US National Cancer Institute National Clinical Trials Network Follicular Lymphoma Clinical Trials. J Clin Oncol 2023; 41:336.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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