Are You at Risk for Upper GI Bleeding?
Published: Aug 14, 2024
Understanding the risk factors for upper gastrointestinal bleeding (UGIB) can help you prevent it. Let's explore what makes some people more likely to experience this condition.
Contents
Common Culprits: Medications and Infections
Certain medications, like nonsteroidal anti-inflammatory drugs (NSAIDs) and low-dose aspirin, are known to increase the risk of UGIB. These drugs can irritate the stomach lining and lead to bleeding. Additionally, infections such as Helicobacter pylori can cause ulcers, a leading cause of UGIB. Treating infections and being cautious with medication use are crucial preventive steps.
Lifestyle Factors: Stress and Diet
Lifestyle choices can also affect your risk of UGIB. Physiological stress and a diet high in acidic foods can contribute to stomach lining damage. Reducing stress through relaxation techniques and maintaining a balanced diet may help in lowering the risk of developing UGIB.

Underlying Health Conditions: The Silent Predisposers
Chronic health conditions like liver disease can also increase the risk of UGIB. Conditions causing portal hypertension, such as cirrhosis, can lead to varices, which are prone to bleeding. Managing these underlying health issues is key to preventing UGIB.
Frequently Asked Questions
NSAIDs and aspirin are common medications that increase UGIB risk.
H. pylori can cause ulcers, leading to UGIB.
Physiological stress can contribute to UGIB by damaging stomach lining.
Yes, liver disease can lead to varices and increased UGIB risk.
The Bottom Line
Identifying and managing risk factors is essential in preventing upper gastrointestinal bleeding.
References
- Lanas A, Perez-Aisa MA, Feu F, et al. A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug use. Am J Gastroenterol 2005; 100:1685.
- Hallas J, Lauritsen J, Villadsen HD, Gram LF. Nonsteroidal anti-inflammatory drugs and upper gastrointestinal bleeding, identifying high-risk groups by excess risk estimates. Scand J Gastroenterol 1995; 30:438.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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