Are NSAIDs Safe for Everyday Use?
Published: Sep 03, 2024
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications worldwide for pain and inflammation. But are they really safe for everyday use?
Contents
Understanding NSAIDs
NSAIDs are popular because they help reduce pain, fever, and inflammation. They work by blocking enzymes called COX-1 and COX-2, which are involved in the production of prostaglandins that promote inflammation and pain. However, this action can also lead to side effects, especially when these drugs are used frequently or at high doses.
Common Side Effects
Using NSAIDs regularly can cause several side effects, including stomach issues like ulcers and bleeding, kidney problems, and increased blood pressure. The risk of these side effects is higher in older adults, those with pre-existing health conditions, and those taking other medications that interact with NSAIDs.

Cardiovascular Concerns
NSAIDs can also affect the heart and blood vessels, potentially increasing the risk of heart attack or stroke, especially in people with existing heart conditions or those who use NSAIDs long-term. Some NSAIDs may interfere with the protective effects of aspirin, which is often used to prevent heart attacks.
Frequently Asked Questions
NSAIDs are drugs that reduce pain, fever, and inflammation.
Yes, they can cause ulcers and bleeding in the stomach.
Yes, they can increase the risk of heart attack or stroke.
Older adults should use NSAIDs cautiously due to increased risk of side effects.
The Bottom Line
While NSAIDs are effective for pain relief, it's important to use them wisely to avoid serious side effects.
References
- Davis JS, Lee HY, Kim J, et al. Use of non-steroidal anti-inflammatory drugs in US adults: changes over time and by demographic. Open Heart 2017; 4:e000550.
- Pirmohamed M, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients. BMJ 2004; 329:15.
This article has been reviewed for accuracy by one of the licensed medical doctors working for Doctronic. Always discuss health information with your healthcare provider.
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