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What Causes Stomach Pain That Wakes You up at Night?
Understanding Nighttime Stomach Pain Causes
March 31st, 2026
What Causes Stomach Pain That Wakes You up at Night?
Nighttime stomach pain is most commonly caused by peptic ulcers, which affect up to 10% of adults at some point in their lives. Stomach acid production naturally increases at night, making ulcer pain worse when lying flat. Gastroesophageal reflux disease (GERD) also worsens at night due to reduced gravity assistance when horizontal. Other causes include gallstones, which cause pain that intensifies 1-3 hours after eating, and gastroparesis, where delayed stomach emptying creates pressure. Inflammatory bowel conditions like Crohn's disease can also cause nocturnal pain flares. The timing and intensity of nighttime stomach pain often indicates the underlying condition, making it important to track patterns and seek medical evaluation for proper diagnosis.
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