What Causes Stomach Pain Above the Belly Button?

Pain above the belly button can have many causes, including indigestion, gastritis, peptic ulcers, or gastroesophageal reflux disease (GERD). The epigastric region houses the stomach and duodenum, making these organs common culprits when upper abdominal discomfort occurs. Gastritis is inflammation of the stomach lining and may be associated with H. pylori infection, NSAID use, or heavy alcohol use. Peptic ulcers can cause burning or aching upper abdominal pain, but symptoms vary and may occur when the stomach is empty or after eating. GERD is common and occurs when stomach contents repeatedly flow back into the esophagus, often causing heartburn or regurgitation. Other causes include gallbladder disease, pancreatitis, or muscle strain. Seek urgent medical care for severe or worsening pain, chest pain, trouble breathing, fainting, persistent vomiting, vomiting blood, black stools, a rigid or swollen abdomen, or pain with fever or yellowing of the skin or eyes.